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Hepatic toxicity and uroporphyrinogen decarboxylase activity following a single dose of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin to mice

✍ Scribed by Andrew G. Smith; Jean E. Francis; Sara J.E. Kay; John B. Greig


Book ID
115775832
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
842 KB
Volume
30
Category
Article
ISSN
0006-2952

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## Abstract The induction response of cytochrome P‐450‐dependent enzyme activities to a single low (5 nmol/kg) or high (50 nmol/kg, intraperitoneal [ip] dose of TCDD was examined in liver and lung homogenates over a 12‐week time course in an outbred, Ah‐responsive strain of mice (National Institute