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Hepatic stimulator substance promotes the epidermal growth factor-induced proliferation of normal adult hepatocytes in primary culture


Book ID
123215882
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
91 KB
Volume
7
Category
Article
ISSN
0168-8278

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Effect of cell density and epidermal gro
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The influence of cell density and epidermal growth factor (EGF) on the expression and inducibility of cytochrome P450 (CYP) genes of the CYP3A and CYP1A families in adult human hepatocytes in primary culture has been evaluated. Only when cultured at subconfluence and in the presence of EGF did hepat