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Hepatic microsomal mixed function oxidase system during toluene treatment and the effect of pretreatment of phenobarbital in adult rats

โœ Scribed by Avinash M. Mungikar; Sitaram S. Pawar


Book ID
112589880
Publisher
Springer
Year
1976
Tongue
English
Weight
425 KB
Volume
15
Category
Article
ISSN
0007-4861

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A drastic impairment in hepatic mixed-function oxidase (MFO) system was observed in rats 24 h following ip injection of CCl 4 (1.0 ml/kg body weight), as indicated by a decrease in the activities of various microsomal enzymes related to drug metabolism (e.g., aniline hydroxylase, aminopyrine-Ndemeth