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Hepatic metabolism of 3-oxoandrost-4-ene-17β-carboxylic acid in the adult rat: formation of carboxyl-linked glucuronides both in vivo and in vitro

✍ Scribed by Anna Radominska; Joanna M. Little; Roger Lester; Jan St. Pyrek


Book ID
116065675
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
775 KB
Volume
57
Category
Article
ISSN
0039-128X

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Metabolism of 24-norlithocholic acid in
✍ Karen E. Shattuck; Anna Radominska-Pyrek; Piotr Zimniak; Eugene W. Adcock; Roger 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 596 KB

## 24-Norlithocholic (3a-hydroxy-24-nor-5/3-cholan-23-oic) acid is the lower homologue of lithocholic acid, a potent cholestatic agent. In order to characterize its cholestatic potential and metabolic fate, 3#?-tritiated 24-norlithocholate was infused intravenously into adult male Sprague-Dawley r