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Hepatic heme metabolism: Possible role of biliverdin in the regulation of heme oxygenase activity

✍ Scribed by R.Krishnan Kutty; Mahin D. Maines

Book ID: 115757425
Publisher: Elsevier Science
Year: 1984
Tongue: English
Weight: 419 KB
Volume: 122
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(84)90436-4

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Induction of heme oxygenase-1 (HO-1) inhibits hepatitis C virus (HCV) replication. Of the products of the reaction catalyzed by HO-1, iron has been shown to inhibit HCV ribonucleic acid (RNA) polymerase, but little is known about the antiviral activity of biliverdin (BV). Herein, we report that BV i