Oxidative mechanisms have been implicated in the pathogenesis of brain edema in acute liver failure (ALF). The aim of this study was to test the hypothesis that inhibition of iron-catalyzed oxidative reactions through iron chelation using deferoxamine could attenuate brain edema in a swine model of
โฆ LIBER โฆ
Hepatic gluconeogenesis and Krebs cycle fluxes in a CCl4 model of acute liver failure
โ Scribed by Rui A. Carvalho; John G. Jones; Chris McGuirk; A. Dean Sherry; Craig R. Malloy
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 101 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0952-3480
- DOI
- 10.1002/nbm.745
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Neutrophil-induced liver injury during endotoxemia is dependent on the adhesion molecule Mac-1 (CD11W CD18) on neutrophils. The potential involvement of its counterreceptor, intercellular adhesion molecule-1 (ICAM-l), in the pathogenesis was investigated after administration of 100 pgikg Salmonella