๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Hepatic extraction, metabolism and biliary excretion of doxorubicin in the isolated prefused rat liver

โœ Scribed by Francois Ballet; Patricia Vrignaud; Jacques Robert; Colette Rey; Raoul Poupon


Publisher
Springer
Year
1987
Tongue
English
Weight
611 KB
Volume
19
Category
Article
ISSN
0344-5704

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Hepatic extraction, metabolism, and bili
โœ Christian Farabos; Marie-Christine Haaz; Pierre Gires; Jacques Robert ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 199 KB ๐Ÿ‘ 2 views

Irinotecan (CPT-11) is a semisynthetic derivative of camptothecine that has proved activity in the treatment of colorectal carcinoma. The metabolites identiยฎed in humans include SN-38, SN-38 glucuronide, and several CYP3A-derived metabolites. We have studied the hepatic extraction, metabolism, and b

Hepatic metabolism and biliary excretion
โœ Alexandra Maier-Salamon; Gabriele Trauner; Romy Hiltscher; Gottfried Reznicek; B ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 172 KB ๐Ÿ‘ 2 views

The study was designed to investigate the hepatic metabolism and transport system of valerenic acid, a main active constituent of valerian, in isolated perfused livers from Wistar and Mrp2-deficient TR(-) rats. After administration of 20 microM valerenic acid, the formation of seven valerenic acid g

Metabolism and disposition of resveratro
โœ Alexandra Maier-Salamon; Birigt Hagenauer; Gottfried Reznicek; Thomas Szekeres; ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 285 KB ๐Ÿ‘ 2 views

In this study, the hepatic metabolism and transport system for resveratrol was examined in isolated perfused livers from Wistar and Mrp2-deficient TR(-) rats. Based on extensive metabolism to six glucuronides and sulfates (M1-M6), the hepatic extraction ratio and clearance of resveratrol was very hi

Dose-dependent inhibition of transporter
โœ Ridhi Parasrampuria; Reza Mehvar ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 192 KB ๐Ÿ‘ 1 views

Methotrexate (MTX) and cyclosporine (CyA) are coadministered in a number of diseases. In this study, the effects of CyA on the hepatobiliary disposition of MTX were investigated in an isolated perfused rat liver model. A bolus 5-mg dose of MTX was added to a recirculating perfusate in the absence or

Strain-related patterns of biliary excre
โœ Hubertus Nederbragt; Aart J. Lagerwerf ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 775 KB

Biliary copper excretion was studied in male, bilecannulated rats of the inbred strains Fischer, Brown Norway, WAG/Rij and Lewis. After intravenous injection of 10,30 and 60 pg copper per 100 gm body weight, two patterns of copper excretion were observed; their profiles varied with the copper dose a