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Hepatic expression of interleukin-12 alters outcome in HCV-infected patients

โœ Scribed by Rai, R.; Anania, F.; Boitnott, J.; Diehl, A.M.; Spoler, C.; Thomas, D.


Book ID
122652020
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
172 KB
Volume
114
Category
Article
ISSN
0016-5085

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The heterogeneity of hepatitis C virus (HCV) is due to the continuous and high replication rate, the low fidelity of the RNA-dependent RNA polymerase, and the immune surveillance of the host. Interleukin-12 (IL-12) plays a central role in mounting an effective cellular immune response directed towar