Hepatic bile acid handling in primary biliary cirrhosis: Effect of ursodeoxycholic acid
β Scribed by Pazzi, Paolo; Scagliarini, Raffaella; Gamberini, Susanna; Prandini, Napoleone; Gullini, Sergio; Jazrawi, Riadh P.
- Book ID
- 123244651
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 171 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0016-5085
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π SIMILAR VOLUMES
Bile acid composition in fasting duodenal bile was assessed at entry and at 2 years in patients with primary biliary cirrhosis (PBC) enrolled in a randomized, doubleblind, placebo-controlled trial of ursodeoxycholic acid (UDCA) (10-12 mg/kg/d) taken as a single bedtime dose. Specimens were analyzed
We have compared the effect of ursodeoxycholic acid with placebo on the clinical state, blood liver chemistries and serum and urinary bile acids in four patients with primary biliary cirrhosis. All parameters were evaluated monthly, and bile acid composition was measured by capillary gas-liquid chro