Hepatic and splenic scintigraphy in idiopathic systemic amyloidosis

✍ Scribed by Bhaskara K. Rao; C. Padmalatha; James Au Buchon; Lionel M. Lieberman

• Book ID: 104683743
• Publisher: Springer
• Year: 1981
• Tongue: English
• Weight: 426 KB
• Volume: 6
• Category: Article
• ISSN: 0340-6997
• DOI: 10.1007/bf00253162

✦ Synopsis

Technetium-99m sulfur colloid (SC) and Technetium-99m pyrophosphate (PYP) scintigrams in a patient with idiopathic systemic amyloidosis were abnormal. Hepatic SC distribution was nonhomogeneous. Spleen showed reduced SC uptake and a large focal defect at its upper pole. Splenic localization of PYP was seen on a bone scan. On histologic examination the abnormal scintigraphic sites showed heavy amyloid deposition. Splenic localization of skeletal radiotracer due to amyloidosis has not been previously reported.