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Heparin reduces serum levels of endothelin-1 and hepatic ischemia reperfusion injury in rabbits

✍ Scribed by Tadashi Matsumoto; Masahiko Yamaguchi; Hiroaki Kikuchi; Hiroshi Nakano; Takemasa Midorikawa; Kaoru Kumada; Minoru Takeda


Book ID
113050299
Publisher
Springer
Year
2000
Tongue
English
Weight
53 KB
Volume
30
Category
Article
ISSN
1436-2813

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✍ Douglas G. Farmer; Fady Kaldas; Dean Anselmo; Masamichi Katori; Xiu-Da Shen; Cha πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 454 KB

This study investigated the effects of dual endothelin (ET) receptor blockade in rat models of liver ischemia and reperfusion injury (IRI). Three models of IRI were used: (1) in vivo total hepatic warm ischemia with portal shunting for 60 minutes with control (saline) and treatment groups (15 mg/kg