Heparin-Controlled Growth of Polypyrrole Nanowires
β Scribed by Wei Shi; Dongtao Ge; Jixiao Wang; Zhizhong Jiang; Lei Ren; Qiqing Zhang
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 269 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1022-1336
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β¦ Synopsis
Abstract
Summary: Heparin, a potent anticoagulant, has been used for the first time for the synthesis of PPy nanowires serving not only as an anion dopant but also as an effective morphologyβdirecting agent. The obtained PPy nanowires exhibit long and fine structures with smooth surface and the average diameter of the nanowires is about 90β100 nm and lengths are several hundred nanometers to micrometers. The possible formation mechanism of PPy nanowires may be related to the chain structure of heparin with functional groups (ο£ΏSO and ο£ΏCOO^β^) on the surface. The effect of concentrations of pyrrole monomers and heparin on the morphology and size of PPy nanowires has been investigated.
SEM image of PPy nanowires synthesized in the presence of heparin.
magnified imageSEM image of PPy nanowires synthesized in the presence of heparin.
π SIMILAR VOLUMES
## Abstract A surface modification technique was developed for the covalent immobilization of poly(vinyl alcohol) (PVA)βheparin hydrogel onto electrically conductive polypyrrole (PPY) film with the objective of achieving controlled release of heparin. First, aldehyde groups were introduced onto PPY
Heparin is a potent anticoagulant which can be immobilized on biomaterial surfaces to increase their hemocompatability. In the present work, we have electrochemically synthesized composites comprising heparin and the electrically conducting polymer polypyrrole. The incorporation and exposure of hepa