Heparanase expression in both normal endometrium and endometrial cancer
β Scribed by ; J. KODAMA; T. KUSUMOTO; N. SEKI; T. MATSUO; Y. OJIMA; K. NAKAMURA; A. HONGO; Y. HIRAMATSU
- Book ID
- 109085830
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 1024 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1048-891X
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A total of 140 endometrial carcinomas (endometrioid type), as well as 72 hyperplasias (41 of simple or complex and 31 of atypical type) and 141 normal endometria (35 in the proliferative and 106 in the secretory phase), were immunohistochemically investigated for expression of the standard and varia
## Abstract ## Background Metastases formation depends on the ability of tumor cells to invade basement membranes in a process involving enzymes capable of degrading extracellular matrix components. ## Methods We examined the expression of heparanase in oral carcinomas and correlated its stainin