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Heparan sulfate proteoglycan expression in cerebrovascular amyloid β deposits in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis (Dutch) brains

✍ Scribed by Jack Horssen; Irene Otte-Höller; Guido David; Marion L. Maat-Schieman; Lambert P. Heuvel; Pieter Wesseling; Robert M. Waal; Marcel M. Verbeek

Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
360 KB
Volume
102
Category
Article
ISSN
0001-6322

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## Abstract The amyloid β‐protein is a 39‐42 amino acid peptide that is deposited in senile plaques and in cerebral vessel walls in individuals with Alzheimer's disease, Down's syndrome, hereditary cerebral hemorrhage with amyloidosis–Dutch type (HCHW A‐D), and, to a much lesser extent, normal agin