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Hemopressin is an inverse agonist of CB1 cannabinoid receptors

โœ Scribed by Heimann, A. S.; Gomes, I.; Dale, C. S.; Pagano, R. L.; Gupta, A.; de Souza, L. L.; Luchessi, A. D.; Castro, L. M.; Giorgi, R.; Rioli, V.; Ferro, E. S.; Devi, L. A.

Book ID
118038204
Publisher
National Academy of Sciences
Year
2007
Tongue
English
Weight
362 KB
Volume
104
Category
Article
ISSN
0027-8424

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An expedient atom-efficient synthesis of
An expedient atom-efficient synthesis of the cannabinoid CB1 receptor inverse agonist ibipinabant
โœ Jos H.M. Lange; Hans J. Sanders; Jeroen van Rheenen ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 314 KB

A novel synthetic route to the highly selective and orally active cannabinoid CB 1 receptor inverse agonist ibipinabant is described which combines the use of inexpensive, commercially available reagents and mild reaction conditions with a high degree of atom-efficiency. The method is expected to en