Hemolytic pattern of erythrocytes in the newborn measured by the coil planet centrifuge system and its relationship to neonatal jaundice
✍ Scribed by Sachio Ogita; Tadahumi Shimamoto; Masanori Ohnishi; Teruji Kamei; Hideharu Noma; Osamu Ishiko; Tetsuji Ando; Tadashi Sugawa
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 408 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0340-6997
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✦ Synopsis
Dynamic osmotic fragility of erythrocytes in cord blood and its changes during the neonatal period were studied by means of a coil planet centrifuge system. The starting-point for hemolysis in the newborn become similar to that of adult blood after approximately a week, while the shift of the end-point to the adult range required one month or more.
The percentage of fragile cord blood cells with a hemolysis starting-point above 110m osmol and the maximum bilirubin level during neonatal period were examined. A high percentage of fragile cells was associated with high bilirubin levels, and when fragile cells comprised more than 7.0% of the total cord blood erythrocytes, the bilirubin level tended to rise above 15 mg/dl.