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Hemolysis in simple shear flows

✍ Scribed by Stephen I. Shapiro; Michael C. Williams

Publisher: American Institute of Chemical Engineers
Year: 1970
Tongue: English
Weight: 645 KB
Volume: 16
Category: Article
ISSN: 0001-1541
DOI: 10.1002/aic.690160412

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✦ Synopsis

Abstract

Whole human blood was sheared in the flow field of a concentric cylinder Couette viscometer in the hope of isolating the physical traumas specifically related to the escape of intracellular hemoglobin. The experimental results indicated that laminar shear stresses per se were not instrumental within the investigated range (up to 600 dynes/sq.cm.). This, plus the hematocrit dependence, evidenced the importance of interaction of individual red cells with a surface in the hemolytic event.

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