Hemoglobins Part B: Biochemical and Analytical Methods

✍ Scribed by Johannes Everse, Kim D. Vandegriff, Robert M. Winslow (Eds.)

Publisher: Academic Press
Year: 1994
Tongue: English
Leaves: 766
Series: Methods in Enzymology 231
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

Hemoglobin has been involved in the most significant advances in our understanding of modern genetics and molecular biology. Now, hemoblobin is again central to a new area: development of artificial blood (blood substitute.) This volume of Methods in Enzymology and its companion, Volume 232, will be indispensable to anyone with a serious interest in this emerging field. They completely update and extend the information presented in Volume 76 published a decade ago.

Key Features
Preparation, purification, and analysis of human hemoglobin and of various non-human hemoglobins
Preparation of hemoglobin hybrids and of model heme compounds
Preparation of chemically modified hemoglobins and of recombinant hemoglobins
Analytical procedures presented for studying hemoglobin stability and degradation and for the formation of xenobiotic adducts of hemoglobin

✦ Table of Contents

Content:
Contributors to volume 231
Pages ix-xiii

Preface
Page xv
Johannes Everse, Kim D. Vandegriff, Robert M. Winslow

Volume in series
Pages xvii-xxx

[1] Pilot-scale preparation of hemoglobin solutions Original Research Article
Pages 3-16
Robert M. Winslow, Keith W. Chapman

[2] Detection of red cell membrane components in human hemoglobin preparations Original Research Article
Pages 17-21
Bernard J.-M. Thevenin, Stephen B. Shohet

[3] Detection of globin chains by reversed-phase high-performance liquid chromatography Original Research Article
Pages 21-44
Bruno Masala, Laura Manca

[4] Structural characterization of hemoglobin variants using capillary electrophoresis and fast atom bombardment mass spectrometry Original Research Article
Pages 45-65
Pasquale Ferranti, Antonio Malorni, Pietro Pucci

[5] Purification of glycated hemoglobin Original Research Article
Pages 65-75
Margo Panush Cohen, Van-Yu Wu

[6] Measurement of endotoxin levels in hemoglobin preparations Original Research Article
Pages 75-91
Robert I. Roth, Jack Levin

[7] Preparation and characterization of insect hemoglobins from Chironomus thummi thummi Original Research Article
Pages 95-111
Hans Heinrich Ruf, Andreas G. AltemГјller, Klaus Gersonde

[8] Preparation and characterization of invertebrate globin complexes Original Research Article
Pages 112-124
Serge N. Vinogradov, Pawan K. Sharma

[9] Fish hemoglobins Original Research Article
Pages 124-150
Alice DeYoung, Laura D. Kwiatkowski, Robert W. Noble

[10] Conformational and functional characteristics of bovine hemoglobin Original Research Article
Pages 150-163
Clara Fronticelli, Enrico Bucci

[11] Synthetic hemes Original Research Article
Pages 167-193
Eishun Tsuchida, Teruyuki Komatsu

[12] Semisynthesis of hemoglobin Original Research Article
Pages 194-215
Rajendra Prasad Roy, A. Seetharama Acharya

[13] Preparation of mixed metal hybrids Original Research Article
Pages 215-222
Antonio Tsuneshige, Takashi Yonetani

[14] Preparation of hemoglobin derivatives selectively or randomly modified at amino groups Original Research Article
Pages 225-246
James M. Manning

[15] Amidation of basic carboxyl groups of hemoglobin Original Research Article
Pages 246-267
M. Janardhan Rao, A. Seetharama Acharya

[16] Bis(pyridoxal) polyphosphates as specific intramolecular cross-linking agents for hemoglobin Original Research Article
Pages 267-274
Ruth E. Benesch

[17] Preparation of intramolecularly cross-linked hemoglobins Original Research Article
Pages 274-280
Roxanne Y. Walder, Mark E. Andracki, Joseph A. Walder

[18] Derivatives of hemoglobin prepared by reaction with aryl or alkyl isothiocyanates Original Research Article
Pages 281-287
Douglas L. Currell

[19] Hemoglobin polymerization Original Research Article
Pages 287-308
Shirley L. MacDonald, Duncan S. Pepper

[20] Preparation of conjugated hemoglobins Original Research Article
Pages 308-322
Hong Xue, J. Tze-Fei Wong

[21] Structural characterization of modified hemoglobins Original Research Article
Pages 322-343
Richard T. Jones

[22] Production of human hemoglobin in Escherichia coli using cleavable fusion protein expression vector Original Research Article
Pages 347-364
Timm-H. Jessen, Noboru H. Komiyama, Jeremy Tame, JosГ©e Pagnier, Daniel Shih, Ben Luisi, Giulio Fermi, Kiyoshi Nagai

[23] Expression of recombinant human hemoglobin in Escherichia coli Original Research Article
Pages 364-374
Douglas Looker, Antony J. Mathews, Justin O. Neway, Gary L. Stetler

[24] Production of Recombinant Human Hemoglobin A in Saccharomyces cerevisiae Original Research Article
Pages 374-390
Jill E. Ogden, Roy Harris, Michael T. Wilson

[25] Purification and characterization of recombinant human sickle hemoglobin expressed in yeast Original Research Article
Pages 390-403
Jose Javier Martin de Llano, Olaf Schneewind, Gary L. Stetler, James M. Manning

[26] Preparation of recombinant hemoglobin in transgenic mice Original Research Article
Pages 403-434
Michael P. Reilly, Steven L. McCune, Thomas M. Ryan, Tim M. Townes, Makoto Katsumata, Toshio Asakura

[27] Transgenic swine as a recombinant production system for human hemoglobin Original Research Article
Pages 435-445
John S. Logan, Michael J. Martin

[28] Detection, formation, and relebance of hemochromes and hemochromes Original Research Article
Pages 449-480
Joseph M. Rifkind, Omoefe Abugo, Abraham Levy, Jane Heim

[29] Measuring relative rates of hemoglobin oxidation and denaturation Original Research Article
Pages 480-490
Victor W. Macdonald

[30] Hydrogen peroxide-mediated ferrylhemoglobin generation in Vitro and in red blood cells Original Research Article
Pages 490-496
Cecilia Giulivi, Kelvin J.A. Davies

[31] The stability of the heme-globin linkage: Measurement of heme exchange Original Research Article
Pages 496-502
Ruth E. Benesch

[32] Release of iron from hemoglobin Original Research Article
Pages 502-514
S. Scott Panter

[33] Thermal denaturation procedures for hemoglobin Original Research Article
Pages 514-524
Kenneth W. Olsen

[34] Photochemical reduction of methemoglobin and methemoglobin derivatives Original Research Article
Pages 524-536
Johannes Everse

[35] Regeneration of functional hemoglobin from partially oxidized hemoglobin in the presence of molecular hydrogen and a multicomponent redox catalyst Original Research Article
Pages 537-544
Evelyn L. Mcgown, Mazhar Khan, Kilian Dill

[36] Peroxidative activities of hemoglobin and hemoglobin derivatives Original Research Article
Pages 547-561
Johannes Everse, Maria C. Johnson, Mario A. Marini

[37] Cyclooxygenase activity of hemoglobin Original Research Article
Pages 562-573
Lucilla Zilletti, Mario Ciuffi, Sergio Franchi-Micheli, Fabio Fusi, Grazia Gentilini, Gloriano Moneti, Massimo Valoti, Gian Pietro Sgaragli

[38] Hydroxylation and dealkylation reactions catalyzed by hemoglobin Original Research Article
Pages 573-598
J.J. Mieyal, D.W. Starke

[39] Oxidation of olefins catalyzed by hemoglobin Original Research Article
Pages 598-621
Giorgio Belvedere, Michele Samaja

[40] Quantitative analysis of hemoglobin-xenobiotic adducts Original Research Article
Pages 625-632
Steven R. Tannenbaum, Paul L. Skipper

[41] Quantitative mass spectrometry of hemoglobin adducts Original Research Article
Pages 632-643
John S. Wishnok

[42] Aromatic amine-hemoglobin adducts Original Research Article
Pages 643-649
Paul L. Skipper, W.G. Stillwell

[43] Epoxide adducts to N-terminal valine of hemoglobin Original Research Article
Pages 650-657
Margareta Tornqvist

[44] Tobacco-specific nitrosamine-hemoglobin adducts Original Research Article
Pages 657-667
Stephen S. Hecht, Steven G.Carmella, Sharon E. Murphy

[45] Benzo[a]pyrene diol epoxide and related polynuclear aromatic hydrocarbon adducts of hemoglobin Original Research Article
Pages 668-674
Koli Taghizadeh, Paul L. Skipper

[46] Analysis of hemoglobin adducts by fluorescence spectroscopy Original Research Article
Pages 674-681
Billy W. Day, Kuldip Singh

Addendum to article [11]
Pages 685-687
Eishum Tsuchida, Teruyuki Komatsu

Author index
Pages 689-718

Subject index
Pages 719-743

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