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Hemoglobin synthesis studies of a family with α-thalassemia trait and sickle cell trait

✍ Scribed by Joseph R. Shaeffer; Joseph DeSimone; Lois J. Kleve

Publisher
Springer
Year
1975
Tongue
English
Weight
304 KB
Volume
13
Category
Article
ISSN
0006-2928

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✦ Synopsis

The ratio of total globin alpha to beta chain synthesis was determined in reticulocytes isolated from the blood of the members of a black family, some of whom had sickle cell trait with low blood HbS concentrations (25-30%). The results support the hypothesis that sickle cell trait individuals with low HbS concentrations also carry a gene for alpha-thalassemia.

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