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Hemoglobin Kenya composed of α- and (Aγβ)-fusion-globin chains, associated with hereditary persistence of fetal hemoglobin

✍ Scribed by Ibifiri Wilcox; Kevin Boettger; Lance Greene; Anita Malek; Lance Davis; Martin H. Steinberg; Hong-Yuan Luo; David H.K. Chui


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
105 KB
Volume
84
Category
Article
ISSN
0361-8609

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We have identified three unrelated individuals and three members of a family with the non-deletion form of A ␥-hereditary persistence of fetal hemoglobin (HPFH). Molecular analysis showed that each individual is a heterozygote for a previously described -195 A ␥ (C→G) mutation. The ␤-globin gene clu