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Hemizygous/homozygous and heterozygous JAK2 mutation detected in plasma of patients with myeloproliferative diseases: correlation with clinical behaviour

✍ Scribed by W. Ma; H. Kantarjian; S. Verstovsek; I. Jilani; M. Gorre; F. Giles; J. Cortes; S. O'Brien; M. Keating; M. Albitar

Book ID: 108673841
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 185 KB
Volume: 134
Category: Article
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.2006.06174.x

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Correlations of JAK2–V617F mutation with

Correlations of JAK2–V617F mutation with clinical and laboratory findings in patients with myeloproliferative disorders

✍ Matthaios Speletas; Eirini Katodritou; Chrisoula Daiou; Eudokia Mandala; Emmanou 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 212 KB

Recently, the acquired mutation JAK2-V617F has been described in the majority of patients with myeloproliferative disorders (MPDs). In this study we evaluated its clinical and laboratory correlates in 166 patients with MPDs. The mutation was detected by allele-specific PCR in 119 patients: 81.4% (35