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Hemispheric brain damage in unilateral status epilepticus

✍ Scribed by Dr Dov Soffer; Eldad Melamed; Yaakov Assaf; Shamay Cotev


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
823 KB
Volume
20
Category
Article
ISSN
0364-5134

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✦ Synopsis


A 20-year-old woman with psychomotor seizures developed prolonged unilateral status epilepticus followed by coma, right hemiparesis, fever, liver failure, and eventually death. Neuropathological findings included severe neuronal ischemic cell change and massive brain edema, essentially restricted to the left cerebral hemisphere. Massive destruction of the hemisphere involved in epileptic activity with sparing of the contralateral hemisphere provides supportive evidence that in humans prolonged seizure activity can cause permanent brain damage.


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