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Hemin inhibits hypertensive rat vascular smooth muscle cell proliferation through regulation of cyclin D and p21

✍ Scribed by Eun Mi Jeon; Hyoung Chul Choi; Kwang Youn Lee; Ki Churl Chang; Young Jin Kang


Book ID
107642015
Publisher
Springer
Year
2009
Tongue
English
Weight
532 KB
Volume
32
Category
Article
ISSN
0253-6269

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## Abstract The mechanism of homocysteine‐induced cell proliferation in human vascular smooth muscle cells (SMCs) remains unclear. We investigated the molecular mechanisms by which homocysteine affects the expression of cyclins A and D1 in human umbilical artery SMCs (HUASMCs). Homocysteine treatme