Disease Causing Hereditary Late-Onset Ataxia with Only Minimal White Matter Changes: A Report of Two Sibs ataxia. Additional-yet not obligate-clinical features (palatal tremor, kyphoscoliosis) and more or less distinctive MRI findings (subtle white matter changes, marked atrophy of brainstem, and sp
Hemichorea and hemiballism associated with contralateral hemiparesis and ipsilateral basal ganglia lesions
β Scribed by Joachim K. Krauss; Thomas Pohle; Jan J. Borremans
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 183 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0885-3185
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β¦ Synopsis
We report on two patients with unilateral hyperkinetic movement disorders associated with contralateral hemiparesis and ipsilateral basal ganglia lesions. The first patient, a 47-year-old woman, had a low-grade astrocytoma located in the right basal ganglia extending into the subthalamic area and the cerebral peduncle. She presented with left hemiparesis, right hemichorea, and intermittent right-sided tremor at rest. The second patient, a 85-year-old woman, had hypertensive hemorrhage to the right posterior basal ganglia, the posterior limb of the internal capsule, the lateral thalamus, and the subtha-lamic region with accompanying intraventricular bleeding. She developed right-sided transient hemichorea-hemiballism. A videotape illustration of one of the patients is provided. The literature on the rare occurrence of ipsilateral hemichoreahemiballism is discussed and possible pathomechanisms are reviewed. We postulate that hemiparesis contralateral to basal ganglia lesions might have a conditioning effect on the appearance of ipsilateral dyskinetic movement disorders.
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We appreciate the careful reading of our manuscript by Okun and colleagues. 1 However, their letter contains a number of inaccuracies that require correction. We clearly state
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