Dopamine transporter: Solubilization fro
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Robert Lew; Dimitri E. Grigoriadis; John Sharkey; Michael J. Kuhar
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Article
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1989
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John Wiley and Sons
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English
โ 443 KB
3H-GBR 12935 was used to label the digitonin-solubilized dopamine transporter from dog caudate nucleus. Specific binding to soluble fractions was observed in dog caudate but was absent in rat cerebellum. Binding to the solubilized transporter sites was saturable and of high affinity (Bmm = 2.57 -+ 0