Increased heme oxygenase-1 gene expressi
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Mercedes Fernandez; Herbert L. Bonkovsky
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Article
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1999
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John Wiley and Sons
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English
β 157 KB
Heme oxygenase (HO) catalyzes the conversion of heme into biliverdin, iron, and carbon monoxide (CO). Two isoforms of HO have been identified: the inducible HO-1 and the constitutive HO-2. CO, like nitric oxide, is an endogenous vasodilator that could contribute to modulation of systemic and local v