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Heme oxygenase-1 prevents superoxide anion-associated endothelial cell sloughing in diabetic rats

✍ Scribed by Shou Quan; Pawel M Kaminski; Liming Yang; Toshisuke Morita; Muneo Inaba; Susumu Ikehara; Alvin I Goodman; Michael S Wolin; Nader G Abraham

Book ID: 116287964
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 484 KB
Volume: 315
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2004.01.086

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## Abstract Proliferative modification of vascular smooth muscle cell (vSMC) and impaired bioavailability of nitric oxide (NO) have both been proposed among the mechanisms linking diabetes and atherosclerosis. However, diabetes induced modifications in phenotype and nitric oxide synthase(s) (NOS) e