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Heme Oxygenase-1 Overexpression Protects Rat Livers from Ischemia/Reperfusion Injury with Extended Cold Preservation

โœ Scribed by Hirohisa Kato; Farin Amersi; Roland Buelow; Judy Melinek; Ana J. Coito; Bibo Ke; Ronald W. Busuttil; Jerzy W. Kupiec-Weglinski

Book ID
114423364
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
406 KB
Volume
1
Category
Article
ISSN
1600-6135

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Native macrophages genetically modified
Native macrophages genetically modified to express heme oxygenase 1 protect rat liver transplants from ischemia/reperfusion injury
โœ Xiu-Da Shen; Bibo Ke; Yoichiro Uchida; Haofeng Ji; Feng Gao; Yuan Zhai; Ronald W ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 903 KB

We investigated whether native macrophages overexpressing heme oxygenase 1 (HO-1) could protect rat orthotopic liver transplant (OLT) against cold ischemia/reperfusion injury (IRI). Livers from Sprague-Dawley rats were stored at 4 C in University of Wisconsin solution for 24 hours, and then they wer