## Abstract Bone resorption is responsible for the morbidity associated with a number of inflammatory diseases such as rheumatoid arthritis, orthopedic implant osteolysis, periodontitis and aural cholesteatoma. Previous studies have established nitric oxide (NO) as a potentially important mediator
Heme-mediated oxygen activation in biology: cytochrome c oxidase and nitric oxide synthase
β Scribed by Thomas L Poulos; Huiying Li; CS Raman
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 910 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1367-5931
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Using clonal derivatives of spontaneous mammary tumours in C3H/HeJ mice, we had earlier shown that tumourβderived nitric oxide (NO), resulting from endothelial type (e) NO synthase (NOS) expression by tumour cells, promoted tumour growth and metastasis by multiple mechanisms: stimulatio
In liver cirrhosis, down-regulation of endothelial nitric oxide synthase (eNOS) has been implicated as a cause of increased intrahepatic resistance. We investigated whether Rho-kinase activation is one of the molecular mechanisms involved in defective eNOS signaling in secondary biliary cirrhosis. L
Recent work indicates that nitric oxide (NO) plays an important role in the systemic and renal alterations of cirrhosis. In the present study, we have evaluated whether the inducible NO synthase (iNOS) isoform participates in the enhanced renal and systemic NO production of a rat model of cirrhosis.
## Abstract We reported previously that low levels of nitric oxide (NO) induced cell death with properties of apoptosis, including chromatin fragmentation and condensation in undifferentiated PC12 pheochromocytoma cells. The present study demonstrates that cytotoxicity of low concentrations of NO i