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Heme binds to factor VIII and inhibits its interaction with activated factor IX

✍ Scribed by Y. REPESSÉ; J. D. DIMITROV; I. PEYRON; E. FARROKHI MOSHAI; L. KIGER; S. DASGUPTA; S. DELIGNAT; M. C. MARDEN; S. V. KAVERI; S. LACROIX-DESMAZES

Book ID
114754770
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
373 KB
Volume
10
Category
Article
ISSN
1538-7933

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Suramin binds to platelet-derived growth
Suramin binds to platelet-derived growth factor and inhibits its biological activity
✍ Markus Hosang 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 494 KB

The polyanion suramin was recently found to inhibit binding of '251-PDGF (platelet-derived growth factor) to Balb/c 3T3 cell membranes. Cultured Swiss 3T3 cells were used to investigate the mode of action of suramin and to monitor its effect on the biological activity of PDGF. Evidence is presented