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Heme and acute inflammation : Role in vivo of heme in the hepatic expression of positive acute-phase reactants in rats

✍ Scribed by Saïd Lyoumi; Hervé Puy; Fabienne Tamion; Catherine Bogard; Antony Leplingard; Michel Scotté; Roger Vranckx; Francis Gauthier; Martine Hiron; Maryvonne Daveau; Yves Nordmann; Jean Charles Deybach; Jean Pierre Lebreton

Book ID
114429767
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
484 KB
Volume
261
Category
Article
ISSN
1432-1327

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Heme oxygenase (HO) is the rate-limiting enzyme in the catabolism of heme to biliverdin, carbon monoxide (CO), and free iron. The enzyme exists as a constitutive isoform (HO-2) and an inducible isoform (HO-1), which is also a stress protein (HSP32). HO-1 has previously been shown to be associated wi