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Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease

✍ Scribed by Barney E. Dwyer; Meghan L. Stone; Nadia Gorman; Peter R. Sinclair; George Perry; Mark A. Smith; Xiongwei Zhu


Book ID
116771480
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
332 KB
Volume
461
Category
Article
ISSN
0304-3940

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Electronic structures of heme a of cytoc
✍ Yu Takano; Haruki Nakamura πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 903 KB

## Abstract The electronic structures of heme __a__ of cytochrome __c__ oxidase in the redox states were studied, using hybrid density functional theory with a polarizable continuum model and a point charge model. We found that the most stable electronic configurations of the d electrons of the Fe