## Abstract High‐dose chemotherapy with autologous stem cell transplantation (ASCT) is curative treatment in various hematologic malignancies. Mobilization and collection of peripheral blood stem cell is the essential part of ASCT. The aim of this study was to evaluate the effectiveness of various
Hematopoietic Growth Factors for Hematopoietic Stem Cell Mobilization and Expansion
✍ Scribed by Robert Möhle; Lothar Kanz
- Book ID
- 117822022
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 162 KB
- Volume
- 44
- Category
- Article
- ISSN
- 1532-8686
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## Abstract Hematopoietic stem cell transplantation (HSCT) has become the standard of care for the treatment of many hematologic malignancies, chemotherapy sensitive relapsed acute leukemias or lymphomas, multiple myeloma; and for some non‐malignant diseases such as aplastic anemia and immunodefici
The introduction of plerixafor has enabled successful collection of stem cells in the majority of patients with lymphoma or myeloma in whom previous attempts at mobilization have failed. However, a proportion of patients have been shown to be resistant to this mobilization regimen. To identify the f