✦ LIBER ✦
Hematologic alterations and CO2 hypersensitivity in male panic disorder patients and normal controls: Similarities to high-altitude hypoxia and chronic lung disease
✍ Scribed by Donald C. Ross; Maurice Preter; Donald F. Klein
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 43 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1091-4269
- DOI
- 10.1002/da.1059
No coin nor oath required. For personal study only.
✦ Synopsis
Patients with panic disorder (PD) may suffer from a hypersensitive suffocation alarm system [Klein, 1993], leading to a pathologic over-reaction to physiologic indicators of potential suffocation. These include decreased plasma oxygen (pO 2 ), increased plasma carbon dioxide (pCO 2 ) concentrations, or increased brain lactate. Many studies have substantiated that heightened CO 2 sensitivity is specifically characteristic of panic disorder and that inhalation of CO 2 produces panic symptoms and attacks [