Helicobacter pylori virulence factors in gastric carcinogenesis
β Scribed by Sicheng Wen; Steven F. Moss
- Book ID
- 116335062
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 320 KB
- Volume
- 282
- Category
- Article
- ISSN
- 0304-3835
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## Abstract Infection with __cagA__βpositive __Helicobacter pylori__ (__H. pylori__) is associated with the development of gastric adenocarcinoma. The __cagA__ gene product CagA is delivered from the bacterium into the cytoplasm of the bacteriumβattached gastric epithelial cell __via__ the typeβIV
Primary non-Hodgkin's lymphomas of the stomach are associated with Helicobacter pylori infection. We analyzed gastric lymphoma onset data with respect to prior H. pylori infections based on the multistage theory of carcinogenesis. This theory provides a link between epidemiological data and biologic