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Helicobacter pylori stimulates p53 oncoprotein expression and apoptesis in gastric epithelium only in the absence of intestinal metaplasia

โœ Scribed by Pronai, Laszlo; Unger, Zsuzsa; Molnar, Bela; Tulassay, Zsolt


Book ID
124106764
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
193 KB
Volume
120
Category
Article
ISSN
0016-5085

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## Background: P53 mutations are an early event in the multistep progression of gastric carcinoma. these mutations are often present in dysplastic and intestinal metaplastic gastric epithelium. however, the presence of immunohistochemically detectable p53 protein and p53 mutations in nondysplastic/