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Helicobacter pylori, a carcinogen, induces the expression of melanoma antigen-encoding gene(Mage)-A3, a cancer/testis antigen

✍ Scribed by Fukuyama, Takashi; Yamazaki, Taiga; Fujita, Tomoko; Uematsu, Takayuki; Ichiki, Yoshinobu; Kaneko, Hiroshi; Suzuki, Tatsuo; Kobayashi, Noritada


Book ID
115523837
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
481 KB
Volume
33
Category
Article
ISSN
1010-4283

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MACE-I has been identified as a human gene, which directs the expression of an antigen being recognized on melanoma cells by autologous cytolytic T cells. MACE-I is expressed in melanomas and some other tumors. It has been proposed that this gene may be linked to the transformation event and therefo