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Helical Peptides Derived from Lactoferrin Bind Hepatitis C Virus Envelope Protein E2

✍ Scribed by Reem Beleid; Donna Douglas; Norman Kneteman; Kamaljit Kaur

Book ID
111368596
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
376 KB
Volume
72
Category
Article
ISSN
1747-0277

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## Abstract Binding of the hepatitis C virus (HCV) envelope protein E2 to CD81 provides a costimulatory signal for human T cells. This phenomenon may play a role in liver damage and autoimmune manifestations associated with HCV infection. Here we show that cross‐linking of CD81 by HCV E2 induced a