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Heightened neurologic complications in children with pandemic H1N1 influenza

✍ Scribed by Jeffrey J. Ekstrand; Amy Herbener; Julia Rawlings; Beth Turney; Krow Ampofo; E. Kent Korgenski; Joshua L. Bonkowsky

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
558 KB
Volume
68
Category
Article
ISSN
0364-5134

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✦ Synopsis

Abstract

The 2009 pandemic influenza A (H1N1) has been recognized to cause neurological complications including seizures and encephalopathy. We identified 18 children with 2009 H1N1 influenza and neurological complications from first and second wave activity, and compared characteristics to seasonal influenza. Seizures, encephalopathy, and status epilepticus were common presentations. Focal neurological symptoms persisted in 22% of patients at discharge. Compared to seasonal influenza, patients with pandemic 2009 influenza were more likely to have encephalopathy, focal neurological findings, aphasia, and abnormal electroencephalographic findings. In addition, we noted a trend toward heightened neurological complications following second wave influenza activity. ANN NEUROL 2010

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