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Hedgehog signalling: How cholesterol modulates the signal

โœ Scribed by Philip W Ingham


Book ID
114317522
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
141 KB
Volume
10
Category
Article
ISSN
0960-9822

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## Abstract The close link between signaling by the developmental regulators of the Hedgehog family and cholesterol biochemistry has been known for some time. The morphogen is covalently attached to cholesterol in a peculiar autocatalytic reaction and embryonal disruption of cholesterol synthesis l