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Heck arylation of styrenes with arenediazonium salts: short, efficient, and stereoselective synthesis of resveratrol, DMU-212, and analogues

✍ Scribed by Angélica Venturini Moro; Flávio Sega P. Cardoso; Carlos Roque D. Correia

Book ID: 104095641
Publisher: Elsevier Science
Year: 2008
Tongue: French
Weight: 179 KB
Volume: 49
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2008.07.087

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✦ Synopsis

Short, efficient, and stereoselective synthesis of the trans-stilbenes resveratrol, DMU-212, and analogues of both compounds are described. The synthesis of these important anti-cancer agents feature the palladium catalyzed Heck-Matsuda arylation of styrenes with arenediazonium tetrafluoroborates.

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