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Heavy-chain directed B-cell maturation: continuous clonal selection beginning at the pre-B cell stage

โœ Scribed by Robert S. Schwartz; B. David Stollar


Book ID
103584110
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
594 KB
Volume
15
Category
Article
ISSN
0167-5699

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## Abstract Reciprocal translocations involving the immunoglobulin loci and the cellular oncogene __MYC__ are hallmark mutations of the human postgerminal center B cell neoplasm, Burkitt's lymphoma. They are occasionally found in other B cell lymphomas, as well. Translocations involving the heavy c