Heating-induced conformational change of a novel β-(1→3)-D-glucan from Pleurotus geestanus

Relationship between conformation and bi

Relationship between conformation and biological response for (1→3)-β-d-glucans in the activation of coagulation Factor G from limulus amebocyte lysate and host-mediated antitumor activity. Demonstration of single-helix conformation as a stimulant.

✍ Hazime Saitô; Yûko Yoshioka; Nobuaki Uehara; Jun Aketagawa; Shigenori Tanaka; Yû 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 734 KB

The relationship between the conformation of (1----3)-beta-D-glucans in gel or hydrated form and the stimulation of two types of biological responses, namely, activation of coagulation Factor G from limulus amebocyte lysate (LAL) and host-mediated antitumor activity was examined. Both types were act