✦ LIBER ✦
Heat stress in the presence of low RNA polymerase activity increases chromosome copy number in Escherichia coli
✍ Scribed by Guzman, Elena C. ;Jimenez-Sanchez, Alfonso ;Orr, Elisha ;Pritchard, Robert H.
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 360 KB
- Volume
- 212
- Category
- Article
- ISSN
- 0026-8925
No coin nor oath required. For personal study only.
✦ Synopsis
A temperature shift-up accompanied by a reduction in RNA polymerase activity in Escherichia coli causes an increased rate of initiation leading to a 1.7- to 2.2-fold increase in chromosome copy number. A temperature shift-up without a reduction in polymerase activity induces only a transient non-scheduled initiation of chromosome replication caused by heat shock with no detectable effect on chromosome copy number.