Down-regulation of FLIP sensitizes rheum
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Guillermo Palao; Begoña Santiago; María Galindo; Mónica Payá; Juan C. Ramirez; J
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Article
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2004
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John Wiley and Sons
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English
⚖ 238 KB
## Abstract ## Objective Hyperplasia of fibroblast‐like synoviocytes (FLS) contributes to chronic inflammation and joint destruction in rheumatoid arthritis (RA). FLICE‐inhibitory protein (FLIP) is an antiapoptotic protein that might prevent apoptotic elimination of FLS in response to death ligand