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Heat-shock protein 72/73 and impaired wound healing in diabetic and hypercortisolemic states

✍ Scribed by Milad S. Bitar; Thameem Farook; Bency John; Issam M. Francis

Book ID
117221372
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
131 KB
Volume
125
Category
Article
ISSN
0039-6060

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Heat shock proteins (hsp) are molecular chaperones that are increased by various environmental and patho-physiological stimuli. Hsp can bind to mutant/wild-type p53 in tumors and, consequently, could not only regulate p53 accumulation or localization but also modulate its biological effects on cells