Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells
โ Scribed by Kinuko Mitani; Hiroyoshi Fujita; Shigeru Sassa; Attallah Kappas
- Book ID
- 115761678
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 372 KB
- Volume
- 165
- Category
- Article
- ISSN
- 0006-291X
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๐ SIMILAR VOLUMES
Exposure of Hep3B cells to metalloporphyrins (tinprotoporphyrin and heme) or cobalt chloride resulted in the production of a significant number of heme oxygenase transcripts, erythropoietin transcripts or both, as indicated by in situ hybridization. Exposure to heme 10 pmol/L resulted in a 30-fold t
In situ hybridization and Northern analysis of heme oxygenase (HO) mRNA was used to determine the induction and expression of HO by various environmental agents. Exposure of Hep3B cells to hemin (1 0 pM) for as little as 5 min resulted in significant production of HO transcripts and mRNA expression