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Heat shock factors and the control of the stress response

✍ Scribed by M.Gabriella Santoro

Book ID: 113994631
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 597 KB
Volume: 59
Category: Article
ISSN: 0006-2952
DOI: 10.1016/s0006-2952(99)00299-3

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The heat shock response is a well-conserved defence mechanism against the accumulation of misfolded proteins due to prolonged elevated heat. The cell responds to heat shock by raising the levels of heat shock proteins (hsp), which are responsible for chaperoning protein refolding. The synthesis of h