Activation of the heat-shock or stress response is generally considered a cytoprotective response to heat or other proteotoxic stresses. In mammalian cells, stressinduced transcription of heat-shock genes is regulated by heat-shock transcription factor 1 (HSF1). We now show that activation of the Fa
Heat shock factor 1 is a transcription factor of Fas gene
β Scribed by E. Shunmei; Yuanbo Zhao; Yunhong Huang; Kun Lai; Cha Chen; Jianming Zeng; Jiangying Zou
- Publisher
- Korean Society for Molecular and Cellular Biology
- Year
- 2010
- Tongue
- English
- Weight
- 360 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1016-8478
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Heat shock transcription factors (HSFs) regulate the expression of heat shock proteins and other molecular chaperones that are involved in cellular processes from higher order assembly to protein degradation and apoptosis. Among the human HSFs, HSFβ4 is expressed as at least two splice
Heat shock transcription factor 2 (HSF-2) activates transcription of heat shock proteins in response to hemin in the human erythroleukemia cell line, K562. To understand the regulation of HSF-2 activation, a series of deletion mutants of HSF-2 fused to the GAL-4 DNA binding domain were generated. We