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HEAT repeats in the Huntington's disease protein

✍ Scribed by Andrade, Miguel A.; Bork, Peer


Book ID
109918257
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
418 KB
Volume
11
Category
Article
ISSN
1061-4036

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Huntington's disease (HD) is a neurodegenerative disorder associated with expansion of CAG trinucleotide repeats in the huntingtin gene. A minimum of 36 CAG repeats is usually reported in patients with clinical features of HD; 30 to 35 repeats represent an intermediate range. Here we report a 65-yea